Pazufloxacin Mesylate CAS 163680-77-1, commonly referred to as PZM, is a synthetic fluoroquinolone antibiotic. It is used to treat infections caused by both Gram-positive and Gram-negative bacteria, such as bronchial and pulmonary infections, bacterial dysentery, urinary tract infections, skin and soft tissue infections, and more.This advanced iteration of the fluoroquinolone class surpasses its predecessor, ciprofloxacin, in terms of efficacy, boasting an extended half-life. In vitro investigations have assessed its antibacterial activity and its potential to impede the growth of specific bacterial strains.
|
Item |
Specification |
Results |
|
Appearance |
Almost White To Light Yellow Crystalline Powder |
Conforms |
|
Related Substances |
Related Substances: Not More Than 1.0% Total Impurities: Not More Than 1.0% |
0.06% 0.2% |
|
PH |
3.0-4.0 |
6.51 |
|
Loss On Drying |
≤1.0% |
0.04% |
|
Residue On Ignition |
≤0.1% |
0.281% |
|
Heavy Metals |
≤0.001% |
0.02% |
|
Assay (Dried Substance) |
75.7%-78.4% |
76.4% |
|
Endotoxin |
<0.5 EU/MG |
<0.5 EU/MG |
|
Microbial Limit |
TAMC ≤10³ CFU/G TYMC ≤10² CFU/G |
150 CFU/G <1×101 CFU/G |

Another Name: Pazufloxacin Methanesulfonate; pazufloxacin mesylate; Pazufloxacin MS; Pazufloxacin MSLT; Pazufloxacin Methanesulphonate; 163680-77-1; Pazufloxacin mesilate; Pazucross; Pazufloxacin (mesylate); Pazufloxaxin methanesulfonate; Pasil; T-3762;
Physical characteristics: A white or pale yellow crystalline powder, odorless, and with a bitter taste. It has a melting point of 256-260°C.
Molecular formula: C17H19FN2O7S
Molecular mass: 414.41
CAS No.: 163680-77-1
MDL Number: MFCD00913262
Pazufloxacin mesylate, with CAS number 163680-77-1, is a fluoroquinolone antibiotic medication that offers several benefits in the treatment of bacterial infections. Here are some of the benefits of Pazufloxacin Mesylate:
1. Broad Spectrum of Activity: Pazufloxacin mesylate exhibits a broad spectrum of activity against various Gram-positive and Gram-negative bacteria. It is effective against common pathogens such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.
2. Urinary Tract Infections: Pazufloxacin mesylate is particularly useful in the treatment of urinary tract infections (UTIs). It can effectively target and eliminate the bacteria responsible for UTIs, providing relief from symptoms such as urinary frequency, urgency, and pain.
3. Respiratory Tract Infections: Pazufloxacin mesylate can be used in the treatment of respiratory tract infections, including pneumonia and bronchitis. It penetrates well into lung tissues, making it effective against respiratory pathogens.
4. Skin and Soft Tissue Infections: Pazufloxacin mesylate is also effective in the treatment of skin and soft tissue infections, such as cellulitis and infected wounds. It helps eliminate or control bacterial growth at the site of infection, reducing inflammation and promoting healing.
5. Limited Development of Antibiotic Resistance: Pazufloxacin mesylate has shown a relatively low rate of resistance development compared to some other fluoroquinolone antibiotics. It remains an important option for the treatment of infections caused by susceptible bacteria.
6. Convenience of Administration: Pazufloxacin mesylate is available in oral and intravenous formulations, providing flexibility in administration based on the severity and location of the infection.
1. Payment term
TT, LC
2. Delivery date
Negotiable
3. Market
Middle East / Africa / Asia / South America / Europe
4. Sample
Available
5. Executive standards
YBH/JP
6. Qualification certificate
Registration "A" status of raw material packaging, Notification of Approval of marketing; COPP DMF
7. Packaging size specification
Inner package: single-layer polyethylene bag and aluminum foil bag.
Outer package: fiber drum.
Packaging size: 25 kg/drum; 1kg/drum; 5kg/drum.
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Pazufloxacin Mesylate API FAQ
Q: What are fluoroquinolone antibiotics used for?
Q: What is the solubility of pazufloxacin?
Q: What is the indication of pazufloxacin?
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