Description

Technical Parameters

Sodium Fusidate is a kind of antibiotic product for curing infections caused by sensitive bacteria especially staphylococci, such as carious osteitis, blood poisoning, encarditis, repeated infected cystic fibrosis, pneumonia, cutaneo-infection & soft tissue infection, surgery infection & wound infection.

Item		Standard Regulation	Test Result
Appearance	Appearance	White or almost white, crystalline powder	White crystalline powder
Impurity	M	≤1.0%	0.14%
	G	≤0.7%	0.13%
	L	≤0.5%	Not detected
	B	≤0.4%	Not detected
	A	≤0.3%	Not detected
	H	≤0.10%	Not detected
	C	≤0.2%	Not detected
	D	≤0.2%	Not detected
	F	≤0.2%	Not detected
	I	≤0.2%	Not detected
	K	≤0.2%	Not detected
	N	≤0.2%	Not detected
	Main unspecified impurities	≤0.10%	Not detected
	Total impurities	≤2.0%	0.27%

Sodium Fusidate CAS 751-94-0

Product: Sodium Fusidate CAS 751-94-0
Chemical Name: Fusidate De Sodium; Fusidato De Sodio; Fuzydyt Alsudium; Natriy Fuzidat; 751-94-0; Fucidina; Fucidine; Fusidatesodium; Fusidin; Fusin; Intertullefucidin; Sodium fusidate reference substance;
CAS No.: 751-94-0
Physical characteristics: A white crystalline powder, and the solvent is a colorless clear liquid.
Molecular formula: C₃₁H₄₇NaO₆
Molecular mass: 538.70
MDL Number: MFCD09054714

Sodium fusidate is obtained by extracting fusidic acid from the fermentation broth of fusidium coccineum, and then salting it with sodium hydroxide. It is a narrow-spectrum and highly effective antibiotic against Gram-positive bacteria widely used abroad. Sodium fusidate has a bactericidal effect by inhibiting bacterial protein synthesis and has a potent antibacterial effect against a range of Gram-positive bacteria. It has been paid more and more attention to maintain strong antibacterial activity and low resistance rate against the vast majority of staphylococcal strains, and has become a new choice for resistant staphylococcus aureus.

Sodium fusidate, with CAS number 751-94-0, is the sodium salt form of fusidic acid, an antibiotic medication. It offers several benefits in the treatment of bacterial infections. Here are some of the benefits of Sodium Fusidate:

1. Broad Spectrum of Activity: Sodium fusidate is effective against a wide range of Gram-positive bacteria, including Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus or MRSA), Streptococcus species, and Corynebacterium species. It inhibits bacterial protein synthesis, thereby preventing bacterial growth and replication.

2. Treatment of Skin Infections: Sodium fusidate is commonly used topically for the treatment of various skin infections, such as impetigo, infected wounds, and infected dermatitis. It helps eliminate or control bacterial growth at the site of infection, reducing inflammation and promoting wound healing.

3. Bone and Joint Infections: Sodium fusidate can be used in the treatment of bone and joint infections caused by susceptible bacteria. It has demonstrated effectiveness in conditions such as osteomyelitis and prosthetic joint infections, particularly when caused by Staphylococcus aureus.

4. Minimal Development of Antibiotic Resistance: Sodium fusidate has shown a relatively low rate of resistance development compared to many other antibiotics. It is considered an important option for the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains that are susceptible to fusidic acid.

5. Combination Therapy: Sodium fusidate can be used in combination with other antibiotics for the treatment of certain infections. It is often used in combination with other agents to improve the effectiveness of treatment, particularly in cases where multidrug-resistant bacteria are involved.

6. Well-Tolerated: Sodium fusidate is generally well-tolerated when used topically or in systemic formulations. Common side effects are usually mild and include skin irritation, itching, or burning sensations at the application site. Systemic side effects are generally rare when used as directed.

1. Payment term

TT, LC

2. Delivery date

Negotiable

3. Market

Middle East / Africa / Asia / South America / Europe

4. Sample

Available
5. Executive standards
CP, EP, IP

6. Qualification certificate
Registration "A" status of raw material packaging, Notification of Approval of marketing application for chemical API, WC, COPP, CEP, EUGMP, US DMF registration number, India Registration certificate, Brazil registration, Malaysia registration, etc.

7. Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 25 kg/drum; 1kg/drum; 5kg/drum.

Our Advantage

We have branch offices in Dubai and India

we have own reliable & Long-term cooperative & experienced factory

Variety products for selection from China and India

We can customize according to your requirements

We can do OEM & ODM

We can offer N-1 to API

Sodium Fusidate API FAQ

Q: Is sodium Fusidate the same as fusidic acid?

A: Yes, sodium fusidate is the sodium salt form of fusidic acid. Fusidic acid and sodium fusidate are essentially the same compound, with sodium fusidate being the salt form of fusidic acid. They both have the same antibiotic properties and are used to treat bacterial infections, including skin infections such as cellulitis and impetigo, as well as eye infections like conjunctivitis.

Q: Is sodium fusidate better than mupirocin?

A: Sodium fusidate was effective in 89% of cases due to Gram-positive cocci, compared with an 83% response to mupirocin. Fusidic acid is recognized as being active against Gram-positive cocci, whereas mupirocin is considered generally to have a broader spectrum of activity.

Q: What is the difference between sodium fusidate and fusidic acid cream?

A: It is suggested that the new 2% fusidic acid cream is particularly suitable for use on lesions requiring no dry dressing, whereas the 2% sodiumfusidate ointment is preferredfor those conditions where a dressing is applied.

Q: Is sodium fusidate good for wounds?

A: Sodium Fusidate can be used on open wound. It is helpful in the treatment of wound infection.

Q: How long do you use sodium Fusidate?

A: Your skin should start to improve after a few days. But it's very important to use the cream or ointment for as long as your doctor has prescribed it. Treatment with fusidic cream or ointment is usually for 1 or 2 weeks, although sometimes it can be for longer.

Q: Is sodium Fusidate a steroid?

A: Micellar properties of sodium fusidate, a steroid antibiotic structurally resembling the bile salts.

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