Description

Technical Parameters

Apalutamide CAS 956104-40-8, Non-steroidal anti-androgen drugs used for the treatment of prostate cancer. Apalutamide works by preventing the hormone testosterone Open a glossary item from stimulating the cancer cells to grow. It also increases the rate of death of cancer cells.

Apalutamide CAS 956104-40-8

Product: Apalutamide CAS 956104-40-8
Another Name: ARN-509; 4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide; ARV-509; ARN509; ARN; Apalutamide (ARN-509); Apalutamide; Apalutamide API; Apalutamide; Intermediates; 956104-40-8; 573762-62-6; 1950587-17-3; 120728-10-1;
Molecular formula: C₂₁H₁₅F₄N₅O₂S
Molecular mass: 477.43
CAS No.: 956104-40-8
EINECS Number: 807-449-9
MDL Number: MFCD22380626

Apalutamide, with CAS number 956104-40-8, is a medication used in the treatment of prostate cancer. Here are some of the benefits of Apalutamide:

1. Treatment of Prostate Cancer: Apalutamide is approved for the treatment of prostate cancer in certain stages. It is specifically used for the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC), which means the cancer has not yet spread to other parts of the body despite hormone therapy (castration).

2. Delaying Metastasis: Apalutamide has been shown to be effective in delaying the spread of prostate cancer to other parts of the body in patients with non-metastatic castration-resistant prostate cancer. By slowing down the progression of the disease, it can provide patients with an extended period before the cancer becomes metastatic.

3. Improved Progression-Free Survival: Apalutamide treatment has demonstrated improvements in progression-free survival for patients with non-metastatic castration-resistant prostate cancer. Progression-free survival refers to the length of time during treatment when the cancer does not worsen or spread.

4. Delaying the Need for Additional Treatment: Apalutamide can help delay the need for additional treatments, such as chemotherapy or radiation therapy, in patients with non-metastatic castration-resistant prostate cancer. By effectively controlling the disease, it provides patients with an extended period without the need for more aggressive interventions.

1. Payment term

TT, LC

2. Delivery date

Negotiable

3. Market

Middle East / Africa / Asia / South America / Europe

4. Sample

Available
5. Executive standards
YBH/JP

6. Qualification certificate

Registration "A" status of raw material packaging, Notification of Approval of marketing

7. Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 25 kg/drum.

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Apalutamide API CAS 956104-40-8 FAQ

Q: Is apalutamide considered chemotherapy?

A: Apalutamide is not considered chemotherapy. It is an antineoplastic drug that belongs to a class called antiandrogen therapy. While it is used in the treatment of cancer, specifically prostate cancer, it works by inhibiting the growth of cancer cells rather than directly attacking them like traditional chemotherapy drugs.

Q: How long can you be on apalutamide for?

A: that apalutamide is to be continued until disease progression or unacceptable toxicity or patient choice to stop treatment. treatment with apalutamide should continue or not will be scheduled to occur at least by the start of the third 4-weekly cycle of treatment.

Q: What is the drug apalutamide used for?

A: Apalutamide is used to treat certain types of prostate cancer (cancer in men that begins in the prostate [a male reproductive gland]) and has spread to other parts of the body or that has not spread to other parts of the body but has not been helped by other medical treatments.

Q: Does apalutamide lower PSA?

A: Conclusions: This real-world study demonstrated that apalutamide initiation is associated with a significantly higher likelihood of achieving ≥90% reduction in PSA as compared to initiation of enzalutamide. Moreover, this deep PSA response was observed to occur earlier with apalutamide treatment than with enzalutamide.

Q: Does apalutamide cause hair loss?

A: Hair thinning.Your hair may become thinner when you are taking this treatment. This is usually mild.

Q: What is the advantage of apalutamide?

A: After a median follow-up of nearly 4 years in the TITAN study, death risk in the apalutamide group was reduced by 35% compared with the placebo group (median OS, NR vs. 52.2 months; HR=0.65, 95 % CI 0.53–0.79; p < 0.0001)

Q: What is the best time of day to take apalutamide?

A: You take apalutamide once a day. You swallow them whole with a glass of water. You can take them either with food or between meals. You continue to take them as long as they are helping and the side effects aren't too bad.

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