Parecoxib Sodium CAS 198470-85-8

Parecoxib Sodium CAS 198470-85-8
Details:
Product: Parecoxib Sodium CAS 198470-85-8
Alternative Name: Parecoxib Sodium; Parecoxib; Parecoxib Sodium API; Parecoxib Sodium API;
Chemical Name: 4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide sodium salt
Molecular formula: C19H18N2O4S·Na
Molecular mass: 392.409
CAS No.: 198470-85-8
EINECS Number: 813-689-5
MDL Number: MFCD04972608
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Description
Technical Parameters

Parecoxib Sodium, with CAS number 198470-85-8, is a pharmaceutical compound that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is a selective cyclooxygenase-2 (COX-2) inhibitor and is primarily used for its analgesic (pain-relieving) and anti-inflammatory properties.

Parecoxib Sodium is a sodium salt of parecoxib, which is a prodrug. It is a medication used for the management of acute postoperative pain and acute pain associated with certain medical conditions. Parecoxib Sodium is administered intravenously and is rapidly converted to its active form, valdecoxib, in the body.

 

Parecoxib Sodium CAS 198470-85-8
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Product: Parecoxib Sodium CAS 198470-85-8

Alternative Name: Parecoxib Sodium; Parecoxib; Parecoxib Sodium API; Parecoxib Sodium API;

Chemical Name: 4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide sodium salt

Molecular formula: C19H18N2O4S·Na
Molecular mass: 392.409
CAS No.: 198470-85-8

EINECS Number: 813-689-5

MDL Number: MFCD04972608

Here are some of the benefits associated with the use of Parecoxib Sodium:

1. Effective Pain Relief: Parecoxib Sodium is primarily used for the management of acute pain, particularly postoperative pain. It can provide significant pain relief, allowing patients to recover more comfortably after surgical procedures or other medical interventions.

 

2. Anti-inflammatory Action: Parecoxib Sodium belongs to the class of selective cyclooxygenase-2 (COX-2) inhibitors, which means it specifically targets the COX-2 enzyme involved in inflammation. By inhibiting COX-2, it helps reduce inflammation and associated symptoms, such as swelling, redness, and heat.

 

3. Rapid Onset of Action: When administered intravenously, Parecoxib Sodium quickly converts to its active form, valdecoxib. This rapid conversion allows for a faster onset of action, providing prompt pain relief and anti-inflammatory effects.

 

4. Short-term Use: Parecoxib Sodium is typically used for short periods, primarily for acute pain management. This makes it suitable for addressing immediate pain needs, such as postoperative or post-procedural pain, rather than long-term chronic pain conditions.

 

5. Reduced Gastrointestinal Risks: Compared to non-selective NSAIDs, which inhibit both COX-1 and COX-2 enzymes, Parecoxib Sodium offers a potential advantage in terms of gastrointestinal safety. By selectively targeting COX-2, it may pose a lower risk of gastrointestinal side effects, such as stomach ulcers and bleeding.

 

6. Intravenous Administration: Parecoxib Sodium is administered intravenously, allowing for precise dosage control and rapid delivery of the medication. This route of administration ensures reliable absorption and distribution throughout the body.

1. Payment term

TT, LC

2. Delivery date

Negotiable

3. Market

Middle East / Africa / Asia / South America / Europe

4. Sample

Available
5. Executive standards
USP/EP

6. Qualification certificate

Registration "A" status of raw material

7. Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 25 kg/drum.

 

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Parecoxib Sodium CAS 198470-85-8 API FAQ

 

Q: What is parecoxib sodium?

A: Parecoxib sodium is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief. It is a COX-2 inhibitor and is administered as an injection.

Q: What conditions or diseases does parecoxib sodium treat?

A: Parecoxib sodium is used to treat acute pain in adults after surgery or a dental procedure.

Q: How does parecoxib sodium work?

A: Parecoxib sodium inhibits the COX-2 enzyme, which reduces the production of prostaglandins that cause inflammation and pain.

Q: What are the possible side effects of parecoxib sodium?

A: The most common side effects include nausea, vomiting, headache, dizziness, and diarrhea. Serious side effects, such as allergic reactions and gastrointestinal bleeding, are rare but can occur.

Q: Who should not take parecoxib sodium?

A: Parecoxib sodium is not suitable for people with a history of allergies to NSAIDs, sulfa drugs, or parecoxib sodium. It is also not recommended for people with severe liver or kidney disease, heart failure, or bleeding disorders.

Q: Is parecoxib sodium safe during pregnancy and breastfeeding?

A: Parecoxib sodium is not recommended for use during pregnancy or breastfeeding, as it may harm the fetus or infant. The potential benefits and risks should be discussed with a healthcare provider.

Q: Can I drive or operate machinery while taking parecoxib sodium?

A: Parecoxib sodium may cause dizziness or drowsiness, so it is not advisable to drive or operate machinery until you know how it affects you.

 

 

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